Urea Breath Test and H.Pylori Test

Fast, Accurate Detection of Helicobacter pylori (H. pylori)

What Is the Urea Breath Test?

The Urea Breath Test is a safe, non-invasive diagnostic procedure that detects Helicobacter pylori (H. pylori) infection in the stomach. It is widely regarded as the gold standard for identifying active H. pylori infections, especially in patients experiencing chronic gastrointestinal discomfort.

It detects active H.Pylori infection, not just exposure. Has sensitivity and specificity >90%*.

At Regis Medical, we provide the Urea Breath Test using Hospital-aligned clinical protocols, ensuring accurate, timely results with minimal discomfort.

*In Asian Population Studies

What Is H. pylori and Why Is It a Concern?

Helicobacter pylori (H. pylori) is a spiral-shaped bacterium that colonises the lining of the stomach. It's estimated that up to 50% of the global population may carry H. pylori—often without any symptoms. However, in some individuals, this bacterium can trigger inflammation, erode the stomach lining, and lead to serious health issues if left untreated.

Potential Complications of H. pylori Infection

  • Chronic gastritis

  • Peptic ulcers (gastric or duodenal)

  • Persistent acid reflux and indigestion

  • Iron deficiency anemia

  • Increased risk of stomach (gastric) cancer

  • Relapse after treatment if not fully eradicated

Early detection and treatment are essential to prevent long-term complications and recurring digestive discomfort.

Symptoms of H. pylori Infection

Many individuals with H. pylori have no noticeable symptoms. When symptoms do occur, they may include:

  • Burning or gnawing stomach pain (often worse on an empty stomach)

  • Bloating or early fullness after eating

  • Nausea or frequent burping

  • Unexplained weight loss

  • Loss of appetite

  • Frequent acid reflux or heartburn

  • Dark or black stools (a possible sign of bleeding ulcers)

If you're experiencing any of these symptoms regularly, your doctor may recommend a Urea Breath Test to confirm H. pylori infection.

How the Urea Breath Test Works

The Urea Breath Test is a non-invasive diagnostic test that detects active H. pylori infection. It works by measuring how H. pylori breaks down a specially formulated urea compound.

Here’s how the test works:

  • You’ll drink a solution containing a harmless urea compound labeled with a special carbon molecule.

  • If H. pylori is present in your stomach, it will metabolize the urea and release carbon dioxide.

  • You’ll then exhale into a collection device. The carbon dioxide in your breath is analyzed for the labeled carbon.

  • A positive result confirms an active H. pylori infection.

Test Process and What to Expect

  • Fasting: No food or drink (except plain water) for 6 hours prior to the test

  • Duration: Approximately 30 to 45 minutes

  • Results: Typically available within 1–3 working days

  • *If checking for H Pylori Eradication, please ensure that you have completed the antibiotics prescribed at least 4 weeks before your test date. If you are on antibiotics for other infection/purposes, please postpone your test. 

  • * Please ensure that you have stopped taking any gastroprotective/gastric medications (e.g. proton pump inhibitors such as Omeprazole, or H2 receptor blockers such as Famotidine, or Bismuth) for at least 2 weeks before the test date (unless you have received special instructions from your doctor not to stop this medication for a specific reason). 

Who Should Consider a Urea Breath Test?

You may benefit from a Urea Breath Test if you:

  • Have persistent digestive symptoms like pain, bloating, nausea, or indigestion

  • Have been diagnosed with gastritis or peptic ulcers

  • Previously tested positive for H. pylori and need post-treatment confirmation

  • Have a family history of stomach (gastric) cancer

  • Prefer a non-invasive alternative to endoscopy, stool, or blood-based tests

Urea Breath Test and H. pylori Testing

Test

Price (SGD)

Turnaround Time

Urea Breath Test

$140

1–3 working days

H. pylori IgG Blood Test

$35

3-5 working days

Whatsapp Us Make an Appointment

*Prices listed were last updated on 1 July 2023. Prices may be subject to change. 

*Price does not include consultation fee and GST.

Book Your Urea Breath Test Today

Early detection can save you from months or even years of discomfort. Don't wait for symptoms to worsen — take charge of your gut health today.

Finding Us

FAQ

Accessibility & Support

What is Regis Medical GP clinic’s locations and opening hours?

Regis Medical Holland Village is located at 255 Holland Avenue, Singapore 278983

Regis Medical Katong is located at 437 Joo Chiat Road, Singapore 427650

Click here to view our opening hours

Appointment

Can I just walk in for a H.Pylori test? 
Yes, you can. However, to avoid long waiting time, we strongly advise you to book your appointments in advance.
How do I book an appointment?   

To book an appointment at Regis Medical Holland Village, please call or whatsapp us 8118 5298

To book an appointment at Regis Medical Katong, please call or whatsapp us 9851 3728

What are Regis Medical’s cancellation and refund policy?  

You can only cancel or change your appointments up to 24 hours before your appointment. You will receive your refund within 3 working days. No refund will be issued for no shows and cancellations within 24 hours before your appointment. However, if you are feeling unwell on the day of the appointment, we allow patients who have their acute illness seen at Regis Medical to reschedule their appointment without extra cost.

This policy is subject to change.

Can I reschedule my appointment?  

Yes. You can reschedule your appointments. However, you need to reschedule your appointment at least 24 hours before your actual appointment time. If you are unwell on the day of the appointment, we will reschedule your appointment at no extra cost if you seek medical attention at our clinic (for non-emergencies only).

What happens if I miss my appointment?  
No refund will be issued for missed appointments.

Finance

What are the modes of payment accepted at Regis Medical?    
We accept Visa/Mastercard/Amex, PayNow, JCB, UnionPay and ApplePay.

General

What is a urea breath test (UBT)?
It’s a simple, non-invasive test to detect active H. pylori infection. You drink a harmless solution containing urea. If H. pylori is present, it breaks this down and releases carbon dioxide, which is detected in your breath.
How accurate is the urea breath test?

It’s very accurate (over 90%) for detecting active infections and is also the preferred test for checking if treatment worked (to confirm eradication).

Do I need to fast before the test?

Yes. You typically need to avoid food and drink (except water) for at least 4–6 hours before the test. Our clinic will give you exact instructions.

Can I take my usual medications before the test?

Stop antibiotics at least 4 weeks before, and proton pump inhibitors (like omeprazole, esomeprazole) at least 2 weeks before the test—otherwise the results may be falsely negative.

Continue most other usual medications, but always check with your doctor.

Is the urea breath test safe?

Yes. It uses a tiny amount of labeled carbon (non-radioactive or very low radioactivity depending on the version), which is completely safe and quickly cleared from your body.

What happens if I test positive for H. pylori?

You’ll be prescribed a combination of antibiotics plus acid-reducing medication (PPI) for about 2 - 3 weeks to eradicate the bacteria.

Will I need a repeat test after treatment?

Yes. It’s recommended to retest at least 4 weeks after finishing antibiotics to ensure H. pylori is gone.

Can H. pylori come back after treatment?

Re-infection is possible but not very common if hygiene and food safety are good. Most people are cured with one course.

Can H. pylori cause cancer?

Long-term untreated H. pylori infection increases the risk of gastric cancer, which is why testing and treatment are important if you have it.

Can children also have H. pylori and do this test?

Yes. H. pylori is often acquired in childhood. Urea breath testing is safe and used in children.