Last updated: 25 Aug 2026

Diabetic retinopathy is the leading cause of preventable blindness among working-age adults in Singapore. Approximately 30 per cent of Singaporeans with diabetes develop it, and of those, around 10 per cent progress to vision-threatening disease. The numbers are large, the consequences are severe, and the condition is almost entirely preventable with early detection.
Yet many Singaporeans with diabetes have never had their eyes screened. Not because screening is unavailable, but because they do not realise their eyes are at risk until damage has already occurred. Diabetic retinopathy develops silently, over years, with no symptoms until vision is actively deteriorating. By that point, treatment can slow further damage but cannot always restore what has been lost.
This is why screening matters more than almost any other aspect of diabetes management.
The retina is the light-sensitive tissue at the back of your eye. It converts light into electrical signals that your brain interprets as vision. The retina is fed by a dense network of tiny blood vessels that supply it with oxygen and nutrients.
In diabetes, chronically elevated blood sugar damages these small blood vessels over time. The vessel walls weaken. They begin to leak fluid, blood, or fatty deposits into the retina. In early stages, this causes no noticeable change in vision. In more advanced stages, the damaged vessels can become blocked entirely, starving parts of the retina of oxygen. The eye responds by growing new, abnormal blood vessels (a process called neovascularisation), but these new vessels are fragile and prone to bleeding into the eye, causing sudden and sometimes permanent vision loss.
This entire process, from early vessel damage to advanced proliferative disease, can take years. During much of that time, you see perfectly well. The damage accumulates behind the scenes, visible only through a detailed retinal examination. This is precisely why you cannot rely on symptoms to tell you whether your eyes are affected.
You might wonder why diabetes affects the eyes so significantly when it is fundamentally a blood sugar condition. The answer lies in the unique vulnerability of the retinal blood vessels.
The retina has one of the highest metabolic rates of any tissue in the body. It needs a constant, abundant blood supply. The vessels that serve it are extremely small and delicate. When blood sugar is persistently elevated, excess glucose damages the endothelial cells that line these tiny vessels. This damage triggers inflammation, thickening of vessel walls, leakage of fluid and proteins into surrounding tissue, and eventually blockage.
The same process affects small blood vessels elsewhere in the body, which is why diabetes also damages the kidneys (diabetic nephropathy) and nerves (diabetic neuropathy). But the retina is particularly susceptible because its vessels are so fine and its oxygen demands so high.
The key risk factors for developing diabetic retinopathy include duration of diabetes (the longer you have had diabetes, the higher your risk), poor blood sugar control (consistently elevated HbA1c accelerates retinal damage), high blood pressure (which compounds vascular stress), high cholesterol (which contributes to vessel wall damage), and smoking (which impairs blood flow and accelerates vascular disease).
Critically, these are the same risk factors that define metabolic syndrome. If you have diabetes alongside uncontrolled blood pressure and abnormal cholesterol, your eyes are at significantly greater risk than if diabetes is your only condition.
Singapore has one of the most advanced diabetic retinopathy screening programmes in the world. The Singapore Integrated Diabetic Retinopathy Programme (SiDRP), established by the Singapore National Eye Centre (SNEC) and Singapore Eye Research Institute (SERI), provides systematic screening across more than 20 centres islandwide.
The programme uses retinal photography, where a specialised camera captures detailed images of the back of your eye through your dilated pupil. These images are transmitted digitally to a centralised reading centre, where trained and accredited readers assess them for signs of diabetic retinopathy. Results are typically available within one business day, often within the hour.
Since its establishment in 2010, SiDRP has conducted over 150,000 eye screenings. Data from the programme shows that approximately half of patients screened do not have referable diabetic retinopathy, meaning their eyes are healthy or have only very mild changes that do not yet require specialist treatment. This is exactly the outcome screening is designed to achieve: catching disease early or confirming its absence, so that management can be adjusted accordingly.
For patients whose screening images show moderate or severe changes, the programme facilitates prompt referral to a specialist ophthalmologist for further assessment and treatment.
If you have diabetes, current guidelines recommend a comprehensive eye examination at least once a year. This applies regardless of whether you have symptoms.
If you have prediabetes, you do not yet need formal diabetic eye screening. But you should know that this will become necessary if your blood sugar progresses to the diabetic range, which is another reason why regular diabetes screening and early intervention matter.
Early-stage diabetic retinopathy (mild non-proliferative retinopathy) does not usually require treatment beyond optimising blood sugar, blood pressure, and cholesterol control. In many cases, improving these metabolic markers can slow or even halt the progression of early retinal changes.
This is the stage where your GP plays a critical role. Tighter blood sugar management (bringing your HbA1c closer to target), better blood pressure control, cholesterol management, and smoking cessation all directly protect your retinal health. These are interventions your GP can manage without requiring a specialist referral.
If retinopathy progresses to a more advanced stage, treatments include laser therapy (photocoagulation) to seal leaking vessels or shrink abnormal new vessels, intravitreal injections (anti-VEGF medications) to reduce fluid leakage and abnormal vessel growth, and in severe cases, vitrectomy surgery to remove blood or scar tissue from the eye.
These treatments can prevent further vision loss and in some cases improve vision, but they work best when the disease is caught before significant damage has occurred. This is the entire rationale for annual screening: catching changes early enough that simpler, less invasive interventions are still effective.
Diabetic retinopathy does not develop in isolation. The same vascular damage occurring in your retina is happening in your kidneys, your heart, and your peripheral nerves. In many ways, your retinal examination is a window into your overall vascular health. If your retinal vessels show signs of damage, it is reasonable to assume that similar processes are occurring elsewhere.
This is why a diagnosis of diabetic retinopathy should prompt a broader conversation about your metabolic health. At Regis Medical, when we identify or learn of early retinopathy in our patients, we use it as an opportunity to review the complete picture: blood sugar control, blood pressure, cholesterol, kidney function, and cardiovascular risk. Managing these factors comprehensively protects not just your eyes but your long-term health.
If you have diabetes, whether Type 1 or Type 2, and you have not had a comprehensive eye examination in the past 12 months, schedule one. This is not optional preventive care. It is a core component of diabetes management.
If you have been recently diagnosed with Type 2 diabetes, request an eye screening at or shortly after diagnosis. Do not assume your eyes are fine simply because your vision feels normal. Diabetic retinopathy is asymptomatic until it has caused damage that may not be fully reversible.
If you are managing diabetes through lifestyle changes and your blood sugar is well controlled, continue annual screening. Good control reduces your risk but does not eliminate it entirely. Even patients with excellent HbA1c levels can develop retinopathy over time.
If you have risk factors for diabetes but have not been formally diagnosed, a health screening at Regis Medical can determine whether your blood sugar, blood pressure, and cholesterol are within safe ranges. Knowing your metabolic status now allows you to take preventive action before complications, including eye complications, have a chance to develop.
Your vision is not something you get back once it is lost. Protecting it starts with a conversation with your doctor.
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